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Can I take GLP-1 with HRT?
Yes. GLP-1 medications and hormone therapy work through separate pathways and have no known interactions. Many perimenopausal women take both safely.
It depends. Legal via licensed 503A pharmacies during the FDA shortage — but the FDA does not review compounded products. Verify the pharmacy status and sourcing.
NAMS recommends starting HRT under age 60 or within 10 years of menopause onset for the best safety profile. Earlier in that window is often better for symptom control.
Discuss with your clinician after reaching goal or if serious side effects appear. Most patients regain 50-60% of lost weight within 12 months of stopping.
Estrogen has anti-inflammatory effects. Its decline triggers low-grade systemic inflammation — showing up as joint stiffness in fingers, hands, and knees.