The detail
The "window of opportunity" frames HRT initiation. Under 60 or <10 years post-menopause, cardiovascular and bone benefits typically outweigh risks for most women. After 60 + >10 years, risk-benefit shifts. Symptomatic women should consider initiation when symptoms impact quality of life, not wait for "severe" symptoms. Consultation with NAMS-certified clinician recommended.
Sources
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