What changed this year
PCOS care moved from generic to phenotype-stratified. Multi-disciplinary models gained traction.
Major studies
Inositol vs metformin RCT
Inositol non-inferior to metformin for cycle restoration in insulin-resistant phenotype. Better tolerance.
GLP-1 for PCOS observational cohort
Significant weight + A1c improvement. Off-label use rising.
Brand changes
- Allara: Expanded to include reproductive endocrinology.
- Beli Health: Launched PCOS-specific care package.
Policy shifts
- AACE published updated PCOS guidelines emphasizing phenotype
- Insurance increasingly covering metformin off-label for PCOS
What to watch next
PCOS subtyping AI tools. GLP-1 PCOS-specific RCT readouts.