Medication guide · Updated 2026
First neurokinin-3 receptor antagonist FDA-approved for hot flashes (2023). Non-hormonal mechanism.
Generic name
fezolinetant
Drug class
other
Brand names
Veozah
Telehealth offering
0 brands
Blocks neurokinin-3 receptor in hypothalamus, normalizing temperature regulation without affecting estrogen levels.
Educational reference only. Not medical advice. Verify dose, indications, and interactions with a licensed prescriber.
Fezolinetant (generic: fezolinetant) is a prescription medication. Available branded formulations include Veozah. Only FDA-approved formulations are available — no compounded equivalent is in widespread clinical use.
Fezolinetant is typically prescribed for patients meeting the medication's clinical indications under supervision of a licensed prescriber. As with all prescription medications, suitability is determined by a licensed clinician based on individual medical history, current medications, and treatment goals.
Average monthly cost runs around $550, though actual pricing depends heavily on strength, pharmacy, and insurance coverage.
Before starting Fezolinetant, ask your prescribing clinician about: your full medication and supplement list (for interaction screening), recent labs that are relevant to the medication's mechanism, monitoring cadence after starting, and what specific outcome they expect to see in the first 4–12 weeks.
First neurokinin-3 receptor antagonist FDA-approved for hot flashes (2023). Non-hormonal mechanism.
Fezolinetant is administered other. Doses depend on indication and patient response. See the brand pages above for program-specific dosing.
Coverage varies wildly by plan tier and indication. Many GLP-1 + HRT medications require prior authorization. Some compounded versions are not insurance-billable. See individual brand pages for coverage status.
Side effects vary. Review the prescribing information and report symptoms to your provider.
Drug-drug interactions matter — especially for HRT + thyroid + GLP-1 combinations. Use our drug interaction checker, and always disclose your full medication list to the prescriber.
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