Multi-Symptom Decision Tree

Weight Gain + Fatigue

Symptoms: Weight gain · Fatigue · Difficulty losing weight. Likely cause: Insulin resistance, thyroid, or peri-meno metabolic shift.

Likely cause

Insulin resistance, thyroid, or peri-meno metabolic shift

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First steps

  1. Full lab panel: TSH, A1c, fasting insulin, lipids
  2. Body composition scan (DXA or InBody)
  3. Track diet + activity 2 weeks

Treatment options

  • Metformin (if insulin resistant)
  • GLP-1 (semaglutide / tirzepatide)
  • Levothyroxine (if hypothyroid)
  • Strength training

When to see doctor

5%+ weight gain in 6 months unexplained. Earlier if fatigue interferes with function.

Browse providers for Insulin resistance, thyroid, or peri-meno metabolic shiftTake the matcher

Other symptom combinations

Hot Flashes + Sleep DisruptionBrain Fog + Mood ChangesIrregular Periods + AcneLow Libido + Vaginal DrynessJoint Pain + Muscle LossHair Loss + FatigueHeavy Bleeding + AnemiaDepression + Anxiety

Informational only — a symptom pattern is not a diagnosis. Only a clinician can diagnose the cause of your symptoms.