The primary and most potent estrogen produced by the ovaries during the reproductive years.
Also known as: E2, 17-beta-estradiol
Estradiol (E2) is the main estrogen made by the ovaries before menopause. Its levels fluctuate across the menstrual cycle and fall as ovarian function declines during perimenopause.
Estradiol is the form of estrogen used in many modern menopausal hormone therapy products, available as a transdermal patch, gel, spray, oral tablet, or vaginal preparation.